Structure of PDB 5yay Chain A

Receptor sequence
>5yayA (length=244) Species: 10090 (Mus musculus) [Search protein sequence]
RYELSEKMLSACNLLKYNIKDPKALASKDMRICLNTLQHDWFRVSSQKSA
VPAMVGDYIAAFEAVSPDVLRYIINMADGNGNTALHYSVSHSNFQIVKLL
LDADVCNVDHQNKAGYTPIMLAALAAVEAEKDMQVVEELFSCGDVNAKAS
QAGQTALMLAVSHGRIDMVKGLLACGADVNIQDDEGSTALMCASEHGHVE
IVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAHLN
3D structure
PDB5yay Structural insights into ankyrin repeat-mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A N1169 N1171 Y1176 N1201 A1203 Y1205 L1210 L1213 Q1243 H1252 E1274 S1276 C1281 E1284 D1306 D1308 I1315 N80 N82 Y87 N112 A114 Y116 L121 L124 Q154 H163 E185 S187 C192 E195 D217 D219 I226
Gene Ontology
Biological Process
GO:0030837 negative regulation of actin filament polymerization

View graph for
Biological Process
External links
PDB RCSB:5yay, PDBe:5yay, PDBj:5yay
PDBsum5yay
PubMed29217769
UniProtE9Q238

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