Structure of PDB 5yat Chain A

Receptor sequence
>5yatA (length=347) Species: 644223 (Komagataella phaffii GS115) [Search protein sequence]
TIPTTQKAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAW
KGDWPLDNKLPLVGGHEGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNC
EYCIQGAESSCAKADLSGFTHDGSFQQYATADATQAARIPKEADLAEVAP
ILCAGITVYKALKTADLRIGQWVAISGAGGGLGSLAVQYAKALGLRVLGI
DGGADKGEFVKSLGAEVFVDFTKTKDVVAEVQKLTNGGPHGVINVSVSPH
AINQSVQYVRTLGKVVLVGLPSGAVVNSDVFWHVLKSIEIKGSYVGNRED
SAEAIDLFTRGLVKAPIKIIGLSELAKVYEQMEAGAIIGRYVVDTSK
3D structure
PDB5yat Investigation of structure and function of mitochondrial alcohol dehydrogenase isozyme III from Komagataella phaffii GS115.
ChainA
Resolution1.745 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C46 T48 H51 H69 C156
Catalytic site (residue number reindexed from 1) C43 T45 H48 H66 C153
Enzyme Commision number 1.1.1.1: alcohol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C46 H69 E70 C156 C43 H66 E67 C153
BS02 ZN A C100 C103 C106 C114 C97 C100 C103 C111
Gene Ontology
Molecular Function
GO:0004022 alcohol dehydrogenase (NAD+) activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:5yat, PDBe:5yat, PDBj:5yat
PDBsum5yat
PubMed29474823
UniProtC4R0S8

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