Structure of PDB 5y95 Chain A

Receptor sequence
>5y95A (length=80) Species: 10090 (Mus musculus) [Search protein sequence]
GSSGSSGVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPG
VIRRVSQLFHEHPDLIVGFNAFLPSGPSSG
3D structure
PDB5y95 A mimetic of the mSin3-binding helix of NRSF/REST ameliorates abnormal pain behavior in chronic pain models.
ChainA
ResolutionN/A
3D
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8TL A A37 Y40 F65 T72 V79 F93 A13 Y16 F41 T48 V55 F69
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:5y95, PDBe:5y95, PDBj:5y95
PDBsum5y95
PubMed28927787
UniProtQ62141|SIN3B_MOUSE Paired amphipathic helix protein Sin3b (Gene Name=Sin3b)

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