Structure of PDB 5y7w Chain A

Receptor sequence
>5y7wA (length=125) Species: 10090 (Mus musculus) [Search protein sequence]
DIFEAQKIEWHEGAHMTGVESFMTKQDTTGKIISIDTSSLRAAGRTGWED
LVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSA
HTKCKLCYPQSPDMQPFIMGIHIID
3D structure
PDB5y7w Targeted Inhibition of the NCOA1/STAT6 Protein-Protein Interaction
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A G270 I273 I275 V292 R293 Y297 F300 R311 G30 I33 I35 V52 R53 Y57 F60 R71
BS02 peptide A N333 G335 N93 G95
Gene Ontology
Molecular Function
GO:0030374 nuclear receptor coactivator activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5y7w, PDBe:5y7w, PDBj:5y7w
PDBsum5y7w
PubMed29090910
UniProtP70365|NCOA1_MOUSE Nuclear receptor coactivator 1 (Gene Name=Ncoa1)

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