Structure of PDB 5y7g Chain A

Receptor sequence
>5y7gA (length=542) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
ALPEPFYYLHNFRAVLAWIGERYADLLDDQERAFIAAFAELPEASQALLV
RMVMRKGTLFREGKLAYAEIGDTRAAVQPLLALGWVDAQPTLELAQLFGL
LKKDELSQLFRDHLGRANLRKDALLERLQPLFPEARRLAEWQADFAEPVY
ELRCMALCDRLRLMYFGNLWQDWSEFVLADLGIYRYESVEFSADSRGFRL
RADVDAYLHLFDCRQRFDLGEPLEELLAGLPGEPYANPWLEGRRVKLLFQ
FAQHCEKQRDFDLAQRLYRQSSHPGARLRAIRSLERGERFAEAHALAREA
SCAPESDAERQGLARLLPRLQGKLGLPRQARAAAPEIDRLDLCLAFPSEP
CSVEWAVREHLEEPGCAVHYVENGLINSLFGLLCWEAIFAAIPGAFFHPF
HSAPADLHSADFRQRRAALFEACLGRLEDGSYRDAIRCRYRDKFGLQSPF
VYWELLGEELLEQALDCLPAAHLRAWFERLLEDIPGNRAGLPDLIQFWPA
QRRYRMVEVKGPGDRLQDNQLRWLQFCREREMPVAVCYVRWH
3D structure
PDB5y7g Structural mechanism of DNA interstrand cross-link unhooking by the bacterial FAN1 nuclease.
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.4.1: phosphodiesterase I.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity
GO:0004519 endonuclease activity
GO:0004527 exonuclease activity
GO:0004528 phosphodiesterase I activity
GO:0008409 5'-3' exonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0017108 5'-flap endonuclease activity
GO:0030145 manganese ion binding
GO:0046872 metal ion binding
GO:0070336 flap-structured DNA binding
Biological Process
GO:0006281 DNA repair
GO:0036297 interstrand cross-link repair

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5y7g, PDBe:5y7g, PDBj:5y7g
PDBsum5y7g
PubMed29514982
UniProtQ9I2N0|FAN1_PSEAE Fanconi-associated nuclease 1 homolog (Gene Name=fan1)

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