Structure of PDB 5y2q Chain A

Receptor sequence
>5y2qA (length=198) Species: 6523 (Lymnaea stagnalis) [Search protein sequence]
DRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVV
FWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQ
LARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREIS
VDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK
3D structure
PDB5y2q X-ray structure of acetylcholine binding protein (AChBP) complexed with a small molecule
ChainA
Resolution2.363 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8L3 A W53 Q55 L112 M114 W52 Q54 L111 M113 BindingDB: Ki=72nM,IC50=106nM
BS02 8L3 A Y89 W143 Y185 C187 Y192 Y88 W142 Y179 C181 Y186 BindingDB: Ki=72nM,IC50=106nM
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity
GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
Biological Process
GO:0006811 monoatomic ion transport
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0034220 monoatomic ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0050877 nervous system process
GO:0060078 regulation of postsynaptic membrane potential
GO:0060079 excitatory postsynaptic potential
Cellular Component
GO:0005576 extracellular region
GO:0016020 membrane
GO:0043005 neuron projection
GO:0043083 synaptic cleft
GO:0045202 synapse
GO:0098794 postsynapse

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Cellular Component
External links
PDB RCSB:5y2q, PDBe:5y2q, PDBj:5y2q
PDBsum5y2q
PubMed
UniProtP58154|ACHP_LYMST Acetylcholine-binding protein

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