Structure of PDB 5y1x Chain A

Receptor sequence
>5y1xA (length=891) Species: 186763 (Plasmodium falciparum FcB1/Columbia) [Search protein sequence]
EPKIHYRKDYKPSGFIINNVTLNINIHDNETIVRSVLDMDISKHNVGEDL
VFDGVGLKINEISINNKKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEV
IIHPETNYALTGLYKSKNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVT
ADKEKYPVLLSNGDKVNEFEIPGGRHGARFNDPHLKPCYLFAVVAGDLKH
LSATYITKYTKKKVELYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEY
DLSRLNLVAVSDFNVGAMENKGLNIFNANSLLASKKNSIDFSYARILTVV
GHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRENLFSEEMTKTVTTRLSHV
DLLRSVQFLEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRMYLTIL
GEEYYKKGFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADNSANLNQYLL
WFSQSGTPHVSFKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLFIPISVG
LINPENGKEMISQTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPVYIED
NLTDEERILLLKYDSDAFVRYNSCTNIYMKQILMNYNEFLKAKNEKLESF
NLTPVNAQFIDAIKYLLEDPHADAGFKSYIVSLPQDRYIINFVSNLDTDV
LADTKEYIYKQIGDKLNDVYYKMFKSLEAKADDLTYFNDESHVDFDQMNM
RTLRNTLLSLLSKAQYPNILNEIIEHSKSPYPSNWLTSLSVSAYFDKYFE
LYDKTYKLSKDDELLLQEWLKTVSRSDRKDIYEILKKLENEVLKDSKNPN
DIRAVYLPFTNNLRRFHDISGKGYKLIAEVITKTDKFNPMVATQLCEPFK
LWNKLDTKRQELMLNEMNTMLQEPNISNNLKEYLLRLTNKL
3D structure
PDB5y1x Crystal structure of Plasmodium falciparum aminopeptidase N in complex with actinonin
ChainA
Resolution1.55 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E463 H496 E497 H500 E519 E572 Y580
Catalytic site (residue number reindexed from 1) E269 H302 E303 H306 E325 E378 Y386
Enzyme Commision number 3.4.11.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H496 H500 E519 H302 H306 E325
BS02 BB2 A V459 G460 A461 E463 R489 H496 E497 H500 E519 Y580 Q1038 V265 G266 A267 E269 R295 H302 E303 H306 E325 Y386 Q844
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5y1x, PDBe:5y1x, PDBj:5y1x
PDBsum5y1x
PubMed
UniProtO96935|AMPN_PLAF7 Aminopeptidase N (Gene Name=M1AAP)

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