Structure of PDB 5xw5 Chain A

Receptor sequence
>5xw5A (length=362) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
IPTTENLRRSVYLDNTIEFLRGRVYLGAYDYTPEDTDELVFFTVEDAIFY
NSFHLDFGPMNIGHLYRFAVIFHEILNDPENANKAVVFYSSASTRQRANA
ACMLCCYMILVQAWTPHQVLQPLAQVDPPFMPFRDAGYSNADFEITIQDV
VYGVWRAKEKGLIDLHSFNLESYEKYEHVEFGDFNVLTPDFIAFASPQED
LNQPFKSVLNFFANNNVQLVVRLNSHLYNKKHFEDIGIQHLDLIFEDGTC
PDLSIVKNFVGAAETIIKRGGKIAVHSKAGLGRTGCLIGAHLIYTYGFTA
NECIGFLRFIRPGMVVGPQQHWLYLHQNDFREWKYTTRISLKPSEAIGGL
YPLISLEEYRLQ
3D structure
PDB5xw5 Structure and dimerization of the catalytic domain of the protein phosphatase Cdc14p, a key regulator of mitotic exit in Saccharomyces cerevisiae
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F47 A130 Y132 E171 D177 D253 S283 K284 A285 L287 G288 R289 F53 A136 Y138 E177 D183 D247 S277 K278 A279 L281 G282 R283
Gene Ontology
Biological Process
GO:0006470 protein dephosphorylation
GO:0016311 dephosphorylation

View graph for
Biological Process
External links
PDB RCSB:5xw5, PDBe:5xw5, PDBj:5xw5
PDBsum5xw5
PubMed28758351
UniProtQ00684|CDC14_YEAST Tyrosine-protein phosphatase CDC14 (Gene Name=CDC14)

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