Structure of PDB 5xtw Chain A

Receptor sequence
>5xtwA (length=443) Species: 9606 (Homo sapiens) [Search protein sequence]
RQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFK
LCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNR
QEKNIMLYKGSGLWSRWKIYGTTDNLCSRGYEAMYTLLGNANGATCAFPF
KFENKWYADCTSAGRSDGWLWCGTTTDYDTDKLFGYCPLKFEGSESLWNK
DPLTSVSYQINSKSALTWHQARKSCQQQNAELLSITEIHEQTYLTGLTSS
LTSGLWIGLNSLSFNSGWQWSDRSPFRYLNWLPGSPSAEPGKSCVSLNPG
KNAKWENLECVQKLGYICKKWPYAGHCYKIHRDEKKIQRDALTTCRKEGG
DLTSIHTIEELDFIISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFT
KWLRGEPSHENNRQEDCVVMKGKDGYWADRGCEWPLGYICKMK
3D structure
PDB5xtw Structural Insights into the pH-Dependent Conformational Change and Collagen Recognition of the Human Mannose Receptor
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A E452 S454 E461 D475 E406 S408 E415 D429
External links
PDB RCSB:5xtw, PDBe:5xtw, PDBj:5xtw
PDBsum5xtw
PubMed29225077
UniProtP22897|MRC1_HUMAN Macrophage mannose receptor 1 (Gene Name=MRC1)

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