Structure of PDB 5xs8 Chain A

Receptor sequence
>5xs8A (length=474) Species: 519441 (Streptobacillus moniliformis DSM 12112) [Search protein sequence]
PKETTIFAMHLGKALDPNLPVFVKAEKDTNIKLVNVASQNQTDQIQAYNL
MLTEGKLPDIVSYELSADLENLGIEGGLIPLEDLINQHAPNLKKFFEENP
RYKKDAVAVDGHIYMIPNYYDYFNIKVSQGYFIRQDWLEKLGLKEPRTVD
ELYTTLKAFREKDPNGNGKKDEVPFFVRANNVRKVLTSLVDLFKASPIWY
EENGMVKYGPAQKEFKHAIKELSKWYKEGLIDEEIFTRGLESRDYLLSNN
LGGATDDWIASTSSYNRNLADKIPGFNLKLVLPYELNGNAKTRHARTTYL
GGWGISKDAKDPVSLIKYFDYWYSVEGRRLWNFGIEGSEYTLVDGKPVFT
DKVLKNPDGKTPLAVLREVGAQYRLGAFQDAQYELGWASESAKAGYKYYM
DNDVVLDELPILKYTKEKSKEFVSIDTAMRAVVEEKAQQWILGSGDIDKE
WDAYIKRLENLGLSKAEQIQNEAF
3D structure
PDB5xs8 Alternative substrate-bound conformation of bacterial solute-binding protein involved in the import of mammalian host glycosaminoglycans.
ChainA
Resolution1.952 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8EX A H36 L37 Y146 R204 K210 W284 L326 L389 R393 H10 L11 Y120 R178 K184 W258 L300 L363 R367 PDBbind-CN: -logKd/Ki=5.41,Kd=3.86uM
BS02 GCD A W284 S287 L389 Q405 Y409 E410 W258 S261 L363 Q379 Y383 E384 PDBbind-CN: -logKd/Ki=5.41,Kd=3.86uM
BS03 CA A D189 N191 N193 K195 D197 E198 D163 N165 N167 K169 D171 E172
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5xs8, PDBe:5xs8, PDBj:5xs8
PDBsum5xs8
PubMed29208901
UniProtD1AWE0

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