Structure of PDB 5xrm Chain A

Receptor sequence

>5xrmA (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]

SLLPVPYTEAASLSTGSTVTIKGRPLACFLNEPYLQVDFHTEMKEESDIV
FHFQVCFGRRVVMNSREYGAAKQQVESKNMPFQDGQEFELSISVLPDKYQ
VMVNGQSSYTFDHRIKPEAVKMVQVWRDISLTKFNVSYLKR

3D structure

PDB

5xrm Galectin-10: a new structural type of prototype galectin dimer and effects on saccharide ligand binding.

Chain

Resolution

1.998 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GOL	A	H53 R67	H52 R66

Gene Ontology

	Molecular Function
GO:0004622	lysophospholipase activity
GO:0005515	protein binding
GO:0030246	carbohydrate binding
GO:0042802	identical protein binding
GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process

	Biological Process
GO:0002667	regulation of T cell anergy
GO:0002724	regulation of T cell cytokine production
GO:0046006	regulation of activated T cell proliferation
GO:0070231	T cell apoptotic process

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0062023	collagen-containing extracellular matrix

External links

PDB	RCSB:5xrm, PDBe:5xrm, PDBj:5xrm
PDBsum	5xrm
PubMed	29293962
UniProt	Q05315\|LEG10_HUMAN Galectin-10 (Gene Name=CLC)