Structure of PDB 5xod Chain A

Receptor sequence
>5xodA (length=193) Species: 9606 (Homo sapiens) [Search protein sequence]
GPDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSE
RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQS
PNCNQRPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCT
IRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM
3D structure
PDB5xod Hydrophobic patches on SMAD2 and SMAD3 determine selective binding to cofactors
ChainA
Resolution1.851 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y268 E270 Y340 G342 G343 N387 F390 A391 L394 A395 Q447 W448 K451 V452 Q455 Y9 E11 Y81 G83 G84 N124 F127 A128 L131 A132 Q184 W185 K188 V189 Q192
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5xod, PDBe:5xod, PDBj:5xod
PDBsum5xod
PubMed29588413
UniProtQ15796|SMAD2_HUMAN Mothers against decapentaplegic homolog 2 (Gene Name=SMAD2)

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