Structure of PDB 5xgv Chain A

Receptor sequence
>5xgvA (length=461) Species: 295838 (Streptomyces rugosporus) [Search protein sequence]
SDTVIIAGGGPVGLMLACELGLAGVDTVVLERHDAPREPSRGGAINATVV
ELFTQRGIMESLRDDGFEFRMAHFAHIPLAPERVPGDRAFSFAVPHAQVE
RRLEERARSLGVRVRRSTEITSVRQTPDGVQVTTGDGEVVEGAYLVGCDG
SASLVREQAGIPFPGVDPDFHGLWGDIKVEPGAPVLERIGARQYELGLCM
VAPIGPDTVRVITGEFDVPSPPADQEVGFDELRAAVARIAGVELDGVPGW
LSRWTATSRQAERYREGRILLAGDAAHTLFPLGGQALGTGIEDAVNLGWK
LAATVQGWAPPSLLDSYHEERHAAGARACASTRAQTTIMRSLARVGELRA
LLTELAGLEEVNAYLVRMVGGIDGSRLPDVPLVTAEGETSVYRLLEAGRG
VLLDLGAGLPAVRHPQVTYVRAEPTNRLDATAVLLRPDGVVAWRAPQDGL
EAALETWFGPA
3D structure
PDB5xgv Structural Insights into a Flavin-Dependent [4 + 2] Cyclase that Catalyzes trans-Decalin Formation in Pyrroindomycin Biosynthesis.
ChainA
Resolution2.099 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.5.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A G11 P12 V13 E32 R33 H34 R42 I121 D150 G151 W175 G274 D275 P282 G285 A287 L288 G10 P11 V12 E31 R32 H33 R41 I120 D149 G150 W174 G273 D274 P281 G284 A286 L287
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0016853 isomerase activity
GO:0071949 FAD binding
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5xgv, PDBe:5xgv, PDBj:5xgv
PDBsum5xgv
PubMed29657086
UniProtK7QRJ5|PYRE3_STRRG Dialkyldecalin synthase (Gene Name=pyrE3)

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