Structure of PDB 5xfr Chain A

Receptor sequence
>5xfrA (length=309) Species: 9606 (Homo sapiens) [Search protein sequence]
CKFEEGQDVLARWSDGLFYLGTIKKINILKQSCFIIFEDSSKSWVLWKDI
QTGAMVCTICQEEYSEAPNEMVICDKCGQGYHQLCHTPHIDCSVIDSDEK
WLCRQCVFATTTKRGGALKKGPNAKALQVMKQTLPYSVADLEWDAGHKTN
VQQCYCYCGGPGDWYLKMLQCCKCKQWFHEACVQCLQKPMLFGDRFYTFI
CSVCSSGPEYLKRLPLQWVDIAHLCLYNLSVIHKKKYFDSELELMTYINE
NWDRLHPGELADTPKSERYEHVLEALNDYKTMFMSGKEIKKKKHLFGLRI
RVPPVPPNV
3D structure
PDB5xfr Polycomb-like proteins link the PRC2 complex to CpG islands
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A W56 Y62 D82 W13 Y19 D39
BS02 ZN A C105 C108 H130 C133 C57 C60 H82 C85
BS03 ZN A C122 C125 C154 C74 C77 C106
BS04 ZN A C219 C222 C249 C252 C171 C174 C201 C204
BS05 ZN A C204 C206 H227 C230 C156 C158 H179 C182
External links
PDB RCSB:5xfr, PDBe:5xfr, PDBj:5xfr
PDBsum5xfr
PubMed28869966
UniProtQ9Y483|MTF2_HUMAN Metal-response element-binding transcription factor 2 (Gene Name=MTF2)

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