Structure of PDB 5xfo Chain A

Receptor sequence
>5xfoA (length=315) Species: 9606 (Homo sapiens) [Search protein sequence]
GPRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLW
KDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPA
PGEGEGTSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLD
WDAGHLSNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLY
GDRFYEFECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDR
EILPFTSENWDSLLLGELSDTPKGERSSRLLSALNSHKDRFISGREIKKR
KCLFGLHARMPPPVE
3D structure
PDB5xfo Polycomb-like proteins link the PRC2 complex to CpG islands
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C107 C110 C136 C139 C82 C85 C111 C114
BS02 ZN A C90 C93 H115 C118 C65 C68 H90 C93
BS03 ZN A C189 C191 H212 C215 C164 C166 H187 C190
BS04 ZN A C204 C207 C234 C237 C179 C182 C209 C212
External links
PDB RCSB:5xfo, PDBe:5xfo, PDBj:5xfo
PDBsum5xfo
PubMed28869966
UniProtO43189|PHF1_HUMAN PHD finger protein 1 (Gene Name=PHF1)

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