Structure of PDB 5xfn Chain A

Receptor sequence
>5xfnA (length=301) Species: 9606 (Homo sapiens) [Search protein sequence]
GPRPRLWEGQDVLARWTDGLLYLGTIKKVDSAREVCLVQFEDDSQFLVLW
KDISPAALPGEELLCCVCRSETVVPGNRLVSCEKCRHAYHQDCHVPRAPA
PSWVCRQCVFAIATKRGGALKKGPYARAMLGMKLSLPYGLKGLDWDAGHL
SNRQQSYCYCGGPGEWNLKMLQCRSCLQWFHEACTQCLSKPLLYGDRFYE
FECCVCRGGPEKVRRLQLRWVDVAHLVLYHLSVCCKKKYFDFDREILPFT
SENWDSLLLGELSDTPKGERSSRLLSALNSHKDRFISGCLFGLHARMPPP
V
3D structure
PDB5xfn Polycomb-like proteins link the PRC2 complex to CpG islands
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C107 C110 C136 C139 C82 C85 C105 C108
BS02 ZN A C90 C93 H115 C118 C65 C68 H90 C93
BS03 ZN A C189 C191 H212 C215 C158 C160 H181 C184
BS04 ZN A C204 C207 C234 C237 C173 C176 C203 C206
External links
PDB RCSB:5xfn, PDBe:5xfn, PDBj:5xfn
PDBsum5xfn
PubMed28869966
UniProtO43189|PHF1_HUMAN PHD finger protein 1 (Gene Name=PHF1)

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