Structure of PDB 5xf4 Chain A

Receptor sequence
>5xf4A (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB5xf4 Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
ChainA
Resolution2.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y41 R42 P43 T45 R63 R72 R83 F84 S86 R116 V117 T118 M120 Y4 R5 P6 T8 R26 R35 R46 F47 S49 R79 V80 T81 M83
BS02 dna A H39 R40 Y41 P43 G44 V46 R49 R63 K64 L65 P66 R69 H2 R3 Y4 P6 G7 V9 R12 R26 K27 L28 P29 R32
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0045296 cadherin binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010467 gene expression
GO:0032200 telomere organization
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:5xf4, PDBe:5xf4, PDBj:5xf4
PDBsum5xf4
PubMed29146919
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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