Structure of PDB 5xas Chain A

Receptor sequence
>5xasA (length=409) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
KIFGMPLPLYAFALITLLLSHFYNALPTDIVGGFAIMFIIGAIFGEIGKR
LPIFNKYIGGAPVMIFLVAAYFVYAGIFTQKEIDAISNVMDKSNFLNLFI
AVLITGAILSVNRRLLLKSLLGYIPTILMGIVGASIFGIAIGLVFGIPVD
RIMMLYVLPIMGGGNGAGAVPLSEIYHSVTGRSREEYYSTAIAILTIANI
FAIVFAAVLDIIGKKHTWLSGEGELVTHRETAVGLVLSTTCFLLAYVVAK
KILPSIGGVAIHYFAWMVLIVAALNASGLCSPEIKAGAKRLSDFFSKQLL
WVLMVGVGVCYTDLQEIINAITFANVVIAAIIVIGAVLGAAIGGWLMGFF
PIESAITAGLCMANRGGSGDLEVLSACNRMNLISYAQISSRLGGGIVLVI
ASIVFGMMI
3D structure
PDB5xas Structural insights into the elevator-like mechanism of the sodium/citrate symporter CitS
ChainA
Resolution3.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NA A I181 M182 G183 G184 G185 M399 A400 N401 I160 M161 G162 G163 G164 M362 A363 N364
BS02 FLC A G185 N186 Y348 R402 G404 S405 R428 G164 N165 Y311 R365 G367 S368 R391
Gene Ontology
Molecular Function
GO:0008514 organic anion transmembrane transporter activity
GO:0015293 symporter activity
GO:0046872 metal ion binding
Biological Process
GO:0006101 citrate metabolic process
GO:0006814 sodium ion transport
GO:0015711 organic anion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5xas, PDBe:5xas, PDBj:5xas
PDBsum5xas
PubMed28566738
UniProtP31602|CITN_KLEPN Citrate/sodium symporter (Gene Name=citS)

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