Structure of PDB 5x9o Chain A

Receptor sequence
>5x9oA (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
LYFQGADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTV
LMACSGLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLRE
GNIMAVMATAMYLQMEHVVDTCRKFIKASE
3D structure
PDB5x9o Discovery of a novel B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor by utilizing structure-based drug design
ChainA
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 80R A N21 R24 L25 R28 N22 R25 L26 R29 MOAD: Kd=5uM
PDBbind-CN: -logKd/Ki=5.30,Kd=5uM
BindingDB: Kd=5000nM
External links
PDB RCSB:5x9o, PDBe:5x9o, PDBj:5x9o
PDBsum5x9o
PubMed28760529
UniProtP41182|BCL6_HUMAN B-cell lymphoma 6 protein (Gene Name=BCL6)

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