Structure of PDB 5x9h Chain A

Receptor sequence
>5x9hA (length=427) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
EVLEEIHPQDLLALWDELKGEHRYVVLTLLPKAKAAEVLSHLSPEEQAEY
LKTLPPWRLREILEELSLDDLADALQAVRKEDPAYFQRLKDLLDPRTRAE
VEALARYEEDEAGGLMTPEYVAVREGMTVEEVLRFLRRAAPDAETIYYIY
VVDEKGRLKGVLSLRDLIVADPRTRVAEIMNPKVVYVRTDTDQEEVARLM
ADYDFTVLPVVDEEGRLVGIVTVDDVLDVLEAEATEDIHKLGAVDVPDLV
YSEAGPVALWLARVRWLVILILTGMVTSSILQGFESVLEAVTALAFYVPV
LLGTGGNTGNQSATLIIRALATRDLDLRDWRRVFLKEMGVGLLLGLTLSF
LLVGKVYWDGHPLLLPVVGVSLVLIVFFANLVGAMLPFLLRRLGVDPALV
SNPLVATLSDVTGLLIYLSVARLLLEA
3D structure
PDB5x9h ATP-dependent modulation of MgtE in Mg(2+) homeostasis
ChainA
Resolution3.598 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A Y170 V183 S185 R187 V206 V207 F227 P231 Y148 V161 S163 R165 V184 V185 F205 P209 PDBbind-CN: -logKd/Ki=3.76,Kd=172uM
BS02 MG A D91 D247 D69 D225
BS03 MG A A223 D226 A201 D204
BS04 MG A D95 G136 D73 G114
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0015095 magnesium ion transmembrane transporter activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006812 monoatomic cation transport
GO:0015693 magnesium ion transport
GO:1903830 magnesium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:5x9h, PDBe:5x9h, PDBj:5x9h
PDBsum5x9h
PubMed28747715
UniProtQ5SMG8|MGTE_THET8 Magnesium transporter MgtE (Gene Name=mgtE)

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