Structure of PDB 5x70 Chain A

Receptor sequence
>5x70A (length=779) Species: 142805 (Rice dwarf virus (isolate O)) [Search protein sequence]
DYCIPNFSQTVNERTIIDIFTICRYRSPLVVFCLSHNELAKKYAQDVSMS
SGTHVHIIDGSVEITVSLYRTFRTIATQLLGRMQIVVFVTVDKSVVSTQV
MKSIAWAFRGSFVELRNQSVDSSTLVSKLENLVSFAPLYNVPKCGPDYYG
PTVYSELLSLATNARTHWYATIDYSMFTRSVLTGFVAKYFNEEAVPIDKR
IVSIVGYNPPYVWTCLRHGIRPTYIEKSLPNPGGKGPFGLILPVIHNPQI
KLLCLDTFMLSTSMNILYIGAYPATHLLSLQLNGWTILAFDPKITSDWTD
AMAKATGAKVIGVSKEFDFKSFSVQANQLNMFQNSKLSVIDDTWVETDYE
KFQSEKQAYFEWLIDRTSIDVRLISMKWNRSKDTSVSHLLALLPQPYGAS
IREMRAFFHKKGASDIKILAAETEKYMDDFTAMSVSDQINTQKFMHCMIT
TVGDALKMDLDGGRAVIASYSLSNSSNSKERVLKFLSDANKAKAMVVFGA
PNTHRLAYAKKVGLVLDSAIKMSKDLITFSNWRDYGYSQSELYDAGYVEI
TIDQMVAYSSDVYNGVGYFANSTYNDLFSWYIPKWYVHKRMLMQDIRLSP
AALVKCFTTLIRNICYVPHETYYRFRGILVDKYLRSKNVDPSQYSIVGSG
SKTFTVLSHFEVPHECGPLVFEASTDVNISGHLLSLAIAAHFVASPMILW
AEQMKYMAVDRMLPPNLDKSLFFDNKVTPSGALQRWHSREEVLLAAEICE
SYAAMMLNNKHSPDIIGTLKSAINLVFKI
3D structure
PDB5x70 Crystal structure of capping enzyme from Rice dwarf virus
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.50: mRNA guanylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Y73 K627 H704 W758 Y69 K605 H682 W736
BS02 rna A D50 V137 D46 V133
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004484 mRNA guanylyltransferase activity
GO:0005525 GTP binding
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0006370 7-methylguanosine mRNA capping
Cellular Component
GO:0030430 host cell cytoplasm
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5x70, PDBe:5x70, PDBj:5x70
PDBsum5x70
PubMed
UniProtP14583|MCE_RDVA Putative mRNA-capping enzyme P5

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