Structure of PDB 5x6m Chain A

Receptor sequence
>5x6mA (length=122) Species: 10090 (Mus musculus) [Search protein sequence]
SPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQ
PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICE
FPFGSKQKEVCINPYHYKRVES
3D structure
PDB5x6m Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A S71 L72 L76 Q77 S79 K82 S60 L61 L65 Q66 S68 K71
BS02 dna A R75 K82 H101 H102 R64 K71 H90 H91
BS03 ZN A C110 C122 H127 C99 C111 H116
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005667 transcription regulator complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5x6m, PDBe:5x6m, PDBj:5x6m
PDBsum5x6m
PubMed26304548
UniProtP97454|SMAD5_MOUSE Mothers against decapentaplegic homolog 5 (Gene Name=Smad5)

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