Structure of PDB 5x4p Chain A

Receptor sequence
>5x4pA (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
LYFQGADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTV
LMACSGLFYSIFTDQLKCNLSVINLDPEINPEGFCILLDFMYTSRLNLRE
GNIMAVMATAMYLQMEHVVDTCRKFIKASE
3D structure
PDB5x4p Discovery of a B-Cell Lymphoma 6 Protein-Protein Interaction Inhibitor by a Biophysics-Driven Fragment-Based Approach
ChainA
Resolution2.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7ZO A N21 L25 R28 N22 L26 R29 MOAD: Kd=9.3uM
PDBbind-CN: -logKd/Ki=5.03,Kd=9.3uM
BindingDB: Kd=9300nM
External links
PDB RCSB:5x4p, PDBe:5x4p, PDBj:5x4p
PDBsum5x4p
PubMed28471657
UniProtP41182|BCL6_HUMAN B-cell lymphoma 6 protein (Gene Name=BCL6)

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