Structure of PDB 5x17 Chain A

Receptor sequence
>5x17A (length=290) Species: 10090 (Mus musculus) [Search protein sequence]
LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSL
KTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGL
AKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYV
LMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYL
NFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNM
3D structure
PDB5x17 Temperature-Sensitive Substrate and Product Binding Underlie Temperature-Compensated Phosphorylation in the Clock
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D128 K130
Catalytic site (residue number reindexed from 1) D126 K128
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
2.7.11.26: [tau protein] kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A G18 I23 A36 K38 E52 Y56 L85 L135 I148 D149 G16 I21 A34 K36 E50 Y54 L83 L133 I146 D147
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5x17, PDBe:5x17, PDBj:5x17
PDBsum5x17
PubMed28886336
UniProtQ9DC28|KC1D_MOUSE Casein kinase I isoform delta (Gene Name=Csnk1d)

[Back to BioLiP]