Structure of PDB 5x03 Chain A

Receptor sequence
>5x03A (length=363) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
DWISFSHMSSDTDHFPIKSWFRCEQKAASRSYRTLGDMSHPQGIYEVRAA
ITRLISLTRGVKCRPEQMIIGAGTQVLMQLLTELLPKEAVYAMEEPGYRR
MYQLLKNAGKQVKTIMLDEKGMSIAEITRQQPDVLVTTPSHQFPSGTIMP
VSRRIQLLNWAAEEPRRYIIEDDYDSEFTYDVDSIPALQSLDRFQNVIYM
GTFSKSLLPGLRISYMVLPPELLRAYKQRGYDLQTCSSLTQLTLQEFIES
GEYQKHIKKMKQHYKEKRERLITALEAEFSGEVTVKGANAGLHFVTEFDT
RRTEQDILSHAAGLQLEIFGMSRFNLKENKRQTGRPALIIGFARLKEEDI
QEGVQRLFKAVYG
3D structure
PDB5x03 Crystal structure of the C-terminal domain of Bacillus subtilis GabR reveals a closed conformation by gamma-aminobutyric acid binding, inducing transcriptional activation
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A T181 Y205 F250 D279 Y281 T309 S311 R319 T74 Y98 F143 D172 Y174 T202 S204 R212
BS02 ABU A H114 R207 Y281 R430 H7 R100 Y174 R323
Gene Ontology
Molecular Function
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5x03, PDBe:5x03, PDBj:5x03
PDBsum5x03
PubMed28412355
UniProtP94426|GABR_BACSU HTH-type transcriptional regulatory protein GabR (Gene Name=gabR)

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