Structure of PDB 5wwf Chain A

Receptor sequence
>5wwfA (length=178) Species: 9606 (Homo sapiens) [Search protein sequence]
EKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFG
FVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLF
VGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDP
VDKIVLQKYHTINGHNAEVRKALSRQEM
3D structure
PDB5wwf Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A E18 K22 F24 D49 V51 M53 F64 F66 K94 A96 V97 R99 H108 E3 K7 F9 D34 V36 M38 F49 F51 K79 A81 V82 R84 H93 PDBbind-CN: Kd=238.1nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:5wwf, PDBe:5wwf, PDBj:5wwf
PDBsum5wwf
PubMed29379020
UniProtP22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoproteins A2/B1 (Gene Name=HNRNPA2B1)

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