Structure of PDB 5wwe Chain A

Receptor sequence
>5wweA (length=174) Species: 9606 (Homo sapiens) [Search protein sequence]
REKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGF
GFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKL
FVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRKKRGFGFVTFDDHDPVD
KIVLQKYHTINGHNAEVRKALSRQ
3D structure
PDB5wwe Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1.
ChainA
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A E18 Q19 K22 F24 D49 V51 M53 R62 F64 F66 A96 V97 R99 S102 H108 E4 Q5 K8 F10 D35 V37 M39 R48 F50 F52 A82 V83 R85 S88 H94 PDBbind-CN: Kd=534.8nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:5wwe, PDBe:5wwe, PDBj:5wwe
PDBsum5wwe
PubMed29379020
UniProtP22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoproteins A2/B1 (Gene Name=HNRNPA2B1)

[Back to BioLiP]