Structure of PDB 5wnm Chain A

Receptor sequence
>5wnmA (length=263) Species: 10090 (Mus musculus) [Search protein sequence]
ALGLLRTFDAGEFAGWEKVGSFGQVYKVRHVHWKTWLAIKCSPSLHVDDR
ERMELLEEAKKMEMAKFRYILPVYGICQEPVGLVMEYMETGSLEKLLASE
PLPWDLRFRIVHETAVGMNFLHCMSPPLLHLNLKPANILLDAHYHVKISD
FGLAKFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADE
KNILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTF
QEITSETEDLCEK
3D structure
PDB5wnm Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity.
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N143 A147 N148 D161
Catalytic site (residue number reindexed from 1) N132 A136 N137 D150
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VX6 A V28 A49 M96 E97 Y98 M99 E100 T101 G102 A147 L150 D161 V19 A38 M85 E86 Y87 M88 E89 T90 G91 A136 L139 D150
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:5wnm, PDBe:5wnm, PDBj:5wnm
PDBsum5wnm
PubMed29706531
UniProtQ9ERK0|RIPK4_MOUSE Receptor-interacting serine/threonine-protein kinase 4 (Gene Name=Ripk4)

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