Structure of PDB 5wkg Chain A

Receptor sequence

>5wkgA (length=280) Species: 9606 (Homo sapiens) [Search protein sequence]

FQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPW
SKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKYPFEIQGIAGCE
LHSGGAIVSFLRGALGGLDFLSVKNASCVPSPEGGSRAQKFCALIIQYQG
IMETVRILLYETCPRYLLGVLNAGKADLQRQVKPEAWLSSGPSPGPGRLQ
LVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWYLRATLDVAD
GEAAGLSCRVKHSSLEGQDIILYWRGSGLN

3D structure

PDB

5wkg A molecular basis of human T cell receptor autoreactivity toward self-phospholipids.

Chain

Resolution

2.06 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	D21	A	F10 I69 Y73 F77 A100 V126 A129 C131 I148 M155 T157 V158 Y169	F7 I66 Y70 F74 A97 V123 A126 C128 I145 M152 T154 V155 Y166
BS02	CUY	A	V12 Q14 F77 E80 F84 F88 I96 G98 L114 F123 L124 F144 Y151 I154	V9 Q11 F74 E77 F81 F85 I93 G95 L111 F120 L121 F141 Y148 I151

External links

PDB	RCSB:5wkg, PDBe:5wkg, PDBj:5wkg
PDBsum	5wkg
PubMed	29054999
UniProt	P29016\|CD1B_HUMAN T-cell surface glycoprotein CD1b (Gene Name=CD1B)

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