Structure of PDB 5wjc Chain A

Receptor sequence
>5wjcA (length=384) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
ELNAEIDLQKTIQEEYKLWKQNVPFLYDLVITHALEWPSLTIQWLPDKKT
IPGTDYSIQRLILGTHTSGNDQNYLQIASVQLPNSYTIEISQKIPHDGDV
NRARYMPQKPEIIATMGEGGNAYIFDTTCHDALTTGEALPQAVLKGHTAE
GFGLCWNPNLPGNLATGAEDQVICLWDVQTQSFTSSETKVISPIAKYHRH
TDIVNDVQFHPQHEALLASVSDDCTLQIHDTRLNPEEEAPKVIQAHSKAI
NAVAINPFNDYLLATASADKTVALWDLRNPYQRLHTLEGHEDEVYGLEWS
PHDEPILASSSTDRRVCIWDLEKIGEEQTPEDAEDGSPELLFMHGGHTNR
ISEFSWCPNERWVVGSLADDNILQIWSPSRVIWG
3D structure
PDB5wjc Mis16 Switches Function from a Histone H4 Chaperone to a CENP-ACnp1-Specific Assembly Factor through Eic1 Interaction.
ChainA
Resolution2.298 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E29 N36 F39 L40 R349 E365 D366 E368 D369 G370 S371 L374 L375 F376 M377 G379 V415 I416 E15 N22 F25 L26 R315 E331 D332 E334 D335 G336 S337 L340 L341 F342 M343 G345 V381 I382
Gene Ontology
Molecular Function
GO:0000510 H3-H4 histone complex chaperone activity
GO:0005515 protein binding
GO:0042393 histone binding
Biological Process
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0034080 CENP-A containing chromatin assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0098654 CENP-A recruiting complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5wjc, PDBe:5wjc, PDBj:5wjc
PDBsum5wjc
PubMed29804820
UniProtO94244|HAT2_SCHPO Histone acetyltransferase type B subunit 2 (Gene Name=mis16)

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