Structure of PDB 5wj8 Chain A

Receptor sequence
>5wj8A (length=210) Species: 9606 (Homo sapiens) [Search protein sequence]
AVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQITYRFNAYTSTQAK
ALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVL
DENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLA
SGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKK
DHILQVTILD
3D structure
PDB5wj8 Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
ChainA
Resolution1.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D1370 G1372 K1374 D1376 D84 G86 K88 D90
BS02 CA A E1301 D1355 E1357 D1390 E15 D69 E71 D104
BS03 CA A E1301 E1357 D1387 E1388 D1390 D1424 E15 E71 D101 E102 D104 D138
BS04 CA A N1389 N1391 D1422 D1424 N1428 D1478 N103 N105 D136 D138 N142 D192
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:5wj8, PDBe:5wj8, PDBj:5wj8
PDBsum5wj8
PubMed30033219
UniProtQ9H251|CAD23_HUMAN Cadherin-23 (Gene Name=CDH23)

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