Structure of PDB 5why Chain A

Receptor sequence

>5whyA (length=418) Species: 203119 (Acetivibrio thermocellus ATCC 27405) [Search protein sequence]

MAMIHKFSMMGTNIVVDVNSGAVHVVDDISFDILDYYKNFTAGEIKNKLA
HKYNADEIDEALREIESLEAEGLLFSESVVKALCLHISHDCNLRCKYCFA
STQRNMMSLEVGKKAIDFLISESGNRKNLEIDFFGGEPMMNFDVVKGIIE
YARQKEKEHNKNFRFTLTTNGLLLNDENIKYINENMQNIVLSIDGRKEVN
DRMRIRIDGSGCYDDILPKFKYVAESRNQDNYYVRGTFTRENMDFSNDVL
HLADEGFRQISVEPVVAAKDSGYDLREEDLPRLFEEYEKLAYEYVKRRKE
GNWFNFFHFMITGCGSGHEYLAVTPEGDIYPCHQFVGNEKFKMGNVKEGV
LNRDIQNYFKNSNVYTKKECDSCWAKFYCSGGCAANSYNFHKDINTVYKV
GCELEKKRVECALWIKAQ

3D structure

PDB

5why Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides.

Chain

Resolution

2.692 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	SF4	A	C344 S346 C362 C413 A414 A415	C314 S316 C332 C383 A384 A385
BS02	SF4	A	C104 L106 C108 C111 G154 N188 R222	C91 L93 C95 C98 G136 N170 R204
BS03	SF4	A	C400 C403 K406 C409 G411 V427 C432	C370 C373 K376 C379 G381 V397 C402
BS04	SAM	A	Y110 F152 G154 E155 T186 T187 N188 S210 R222 R253 V283 V284	Y97 F134 G136 E137 T168 T169 N170 S192 R204 R235 V265 V266
BS05	CA	A	E174 N180	E156 N162

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

View graph for
Molecular Function

External links

PDB	RCSB:5why, PDBe:5why, PDBj:5why
PDBsum	5why
PubMed	28704043
UniProt	A3DDW1

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