Structure of PDB 5whk Chain A

Receptor sequence
>5whkA (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
HLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVS
WYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTA
KFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFS
CPHRLREHLWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNG
LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVE
LESP
3D structure
PDB5whk Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NHE A S40 G43 E72 S37 G40 E64
BS02 NHE A Y9 E64 D67 F154 R162 Y6 E56 D59 F146 R154
External links
PDB RCSB:5whk, PDBe:5whk, PDBj:5whk
PDBsum5whk
PubMed28878017
UniProtP55899|FCGRN_HUMAN IgG receptor FcRn large subunit p51 (Gene Name=FCGRT)

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