Structure of PDB 5wgg Chain A

Receptor sequence

>5wggA (length=440) Species: 203119 (Acetivibrio thermocellus ATCC 27405) [Search protein sequence]

MAMIHKFSMMGTNIVVDVNSGAVHVVDDISFDILDYYKNFTAGEIKNKLA
HKYNADEIDEALREIESLEAEGLLFSEDPYKEYVSSMDRKSVVKALCLHI
SHDCNLRCKYCFASRNMMSLEVGKKAIDFLISESGNRKNLEIDFFGGEPM
MNFDVVKGIIEYARQKEKEHNKNFRFTLTTNGLLLNDENIKYINENMQNI
VLSIDGRKEVNDRMRIRIDGSGCYDDILPKFKYVAESRNQDNYYVRGTFT
RENMDFSNDVLHLADEGFRQISVEPVVAAKDSGYDLREEDLPRLFEEYEK
LAYEYVKRRKEGNWFNFFHFMIDLTQIVKRLTGCGSGHEYLAVTPEGDIY
PCHQFVGNEKFKMGNVKEGVLNRDIQNYFKNSNVYTKKECDSCWAKFYCS
GGCAANSYNFHKDINTVYKVGCELEKKRVECALWIKAQEM

3D structure

PDB

5wgg Structural Insights into Thioether Bond Formation in the Biosynthesis of Sactipeptides.

Chain

Resolution

2.036 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	A	G21 A22 V23 H24 V25 V26 D27 S30 E57 E60 A61 E64 I65 E281 L331	G21 A22 V23 H24 V25 V26 D27 S30 E57 E60 A61 E64 I65 E274 L324
BS02	SF4	A	C344 S346 C362 C413 A415	C334 S336 C352 C403 A405
BS03	SF4	A	C104 L106 C108 C111 G154 N188 R222	C104 L106 C108 C111 G147 N181 R215
BS04	SF4	A	C400 C403 C409 C432	C390 C393 C399 C422
BS05	SAM	A	Y110 C111 F152 G154 E155 T186 T187 N188 S210 R222 R253 T255 V283 V284	Y110 C111 F145 G147 E148 T179 T180 N181 S203 R215 R246 T248 V276 V277

Gene Ontology

	Molecular Function
GO:0003824	catalytic activity
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

View graph for
Molecular Function

External links

PDB	RCSB:5wgg, PDBe:5wgg, PDBj:5wgg
PDBsum	5wgg
PubMed	28704043
UniProt	A3DDW1

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