Structure of PDB 5wfi Chain A

Receptor sequence
>5wfiA (length=301) Species: 11142 (Murine hepatitis virus strain A59) [Search protein sequence]
NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSAIYKG
KVFFQYSDLSEADLVAVKDAFGFDEPQLLKYYTMLGMCKWPVVVCGNYFA
FKQSNNNSYINVACLMLQHLSLKFPKWQWQEAWNEFRSGKPLRFVSLVLA
KGSFKFNEPSDSIDFMRVVLREADLSGATCNLEFVCKCGVKQEQRKGVDA
VMHFGTLDKGDLVRGYNIACTCGSKLVHCTQFNVPFLICSNTPEGRKLPD
DVVAANIFTGGSVGHYTHVKCKPKYQLYDACNVNKVSEAKGNFTDCLYLK
N
3D structure
PDB5wfi X-ray structure of MHV PLP2 (Cys1716Ser) catalytic mutant in complex with free ubiquitin
ChainA
Resolution1.851 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.50: mRNA guanylyltransferase.
3.1.13.-
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
4.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C1794 C1796 C1828 C1830 C186 C188 C220 C222
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5wfi, PDBe:5wfi, PDBj:5wfi
PDBsum5wfi
PubMed
UniProtP0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab (Gene Name=rep)

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