Structure of PDB 5wew Chain A

Receptor sequence
>5wewA (length=140) Species: 1420013 (Klebsiella pneumoniae 30684/NJST258_2) [Search protein sequence]
MLSGLNHLTLAVSQLAPSVAFYQQLLGMTLHARWDSGAYLSCGDLWLCLS
LDPQRRVTPPEESDYTHYAFSISEADFASFAARLEAAGVAVWKLNRSEGA
SHYFLDPDGHKLELHVGSLAQRLAACREQPYKGMVFFEQH
3D structure
PDB5wew Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens.
ChainA
Resolution3.178 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H67 E113 H67 E113
BS02 A81 A Y65 H67 R122 Y131 Y65 H67 R122 Y131 PDBbind-CN: -logKd/Ki=6.74,Kd=180nM
BS03 A81 A H7 T9 Y39 W46 C48 H7 T9 Y39 W46 C48 PDBbind-CN: -logKd/Ki=6.74,Kd=180nM
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5wew, PDBe:5wew, PDBj:5wew
PDBsum5wew
PubMed30642934
UniProtW8UNW6

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