Structure of PDB 5wet Chain A

Receptor sequence
>5wetA (length=273) Species: 10090 (Mus musculus) [Search protein sequence]
SHSLRYFVTAVSRPGFGEPRYMEVGYVDNTEFVRFDSDAENPRYEPRARW
IEQEGPEYWERETRRAKGNEQCFRVDLRTALRYYNQSAGGSHTLQWMAGC
DVESDGRLLRGYWQFAYDGCDYIALNEDLKTWTAADMAAQITRRKWEQAG
AAERDRAYLEGECVEWLRRYLKNGNATLLRTDPPKAHVTHHRRPEGDVTL
RCWALGFYPADITLTWQLNGEELTQEMELVETRPAGDGTFQKWASVVVPL
GKEQKYTCHVEHEGLPEPLTLRW
3D structure
PDB5wet Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation.
ChainA
Resolution2.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 R62 E63 R66 N70 C73 W97 R155 Y159 E163 W167 Y171 Y6 R61 E62 R65 N69 C72 W96 R154 Y158 E162 W166 Y170
BS02 GLY A D77 K146 W147 D76 K145 W146
BS03 LEU A D77 Y84 Y123 T143 K146 D76 Y83 Y122 T142 K145
External links
PDB RCSB:5wet, PDBe:5wet, PDBj:5wet
PDBsum5wet
PubMed29025991
UniProtP01900|HA12_MOUSE H-2 class I histocompatibility antigen, D-D alpha chain (Gene Name=H2-D1)

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