Structure of PDB 5wep Chain A

Receptor sequence
>5wepA (length=138) Species: 562 (Escherichia coli) [Search protein sequence]
MLQGLNHLTLAVSDLASSLAFYQQLPGMRLHASWDSGAYLSCGALWLCLS
LDEQRRKTPPQESDYTHYAFSVAEEEFAGVVALLAQAGAEVWKDNRSEGA
SYYFLDPDGHKLELHVGNLAQRLAACRERPYKGMVFFD
3D structure
PDB5wep Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens.
ChainA
Resolution3.502 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A81 A H7 T9 W34 Y39 W46 C48 H7 T9 W34 Y39 W46 C48 PDBbind-CN: -logKd/Ki=6.36,Kd=440nM
BS02 ZN A H67 E113 H67 E113
BS03 A81 A Y65 H67 Y131 Y65 H67 Y131 PDBbind-CN: -logKd/Ki=6.36,Kd=440nM
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5wep, PDBe:5wep, PDBj:5wep
PDBsum5wep
PubMed30642934
UniProtD7UQM0

[Back to BioLiP]