Structure of PDB 5wdl Chain A

Receptor sequence
>5wdlA (length=372) Species: 435591 (Parabacteroides distasonis ATCC 8503) [Search protein sequence]
GFVFTTVKENPITSVKNQNRAGTCWCYSSYSFLESELLRMGKGEYDLSEM
FTVYNTYLDRADAAVRTHGDVSFSQGGSFYDALYGMETFGLVPEEEMRPG
MMYADTLSNHTELSALTDAMVAAIAKGKLRKLQSDENNAMLWKKAVAAVH
QIYLGVPPEKFTYKGKEYTPKSFFESTGLKASDYVSLTSYTHHPFYTQFP
LEIQDNWRHGMSYNLPLDEFMEVFDNAINTGYTIAWGSDVSESGFTRDGV
AVMPDDEKVQELSSDMAHWLKLKPEEKKLNTKPQPQKWCTQAERQLAYDN
YETTDDHGMQIYGIAKDQEGNEYYMVKNSWGTNSKYNGIWYASKAFVRYK
TMNIVVHKDALPKAIKAKLGIK
3D structure
PDB5wdl A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro.
ChainA
Resolution2.625 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 R33 A G54 C56 G108 G109 D237 D338 D339 H340 G22 C24 G76 G77 D205 D305 D306 H307 PDBbind-CN: -logKd/Ki=6.17,Ki=683nM
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0046872 metal ion binding
GO:0070005 cysteine-type aminopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0009636 response to toxic substance
GO:0043418 homocysteine catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:5wdl, PDBe:5wdl, PDBj:5wdl
PDBsum5wdl
PubMed30085657
UniProtA6LE66

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