Structure of PDB 5wde Chain A

Receptor sequence
>5wdeA (length=320) Species: 9606 (Homo sapiens) [Search protein sequence]
NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDK
VFSPQASQQDVFQEVQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAEN
PGINQRALQLLFSEVQEKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKL
EIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGHTNRTTEFTNLNEHS
SRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSERVGKEGSRLREAQHI
NKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSP
VEKNTSETLYSLKFAERVRS
3D structure
PDB5wde Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A R451 P454 T456 T530 G531 G533 K534 T535 Y536 R7 P10 T12 T86 G87 G89 K90 T91 Y92
Gene Ontology
Molecular Function
GO:0003777 microtubule motor activity
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0007018 microtubule-based movement

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Molecular Function
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Biological Process
External links
PDB RCSB:5wde, PDBe:5wde, PDBj:5wde
PDBsum5wde
PubMed29123223
UniProtQ9BVG8|KIFC3_HUMAN Kinesin-like protein KIFC3 (Gene Name=KIFC3)

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