Structure of PDB 5wct Chain A

Receptor sequence
>5wctA (length=177) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]
MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSD
GGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIE
IGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRA
RIKTRLFTIRQEMASRSLWDSFRQSER
3D structure
PDB5wct Protein-Structure Assisted Optimization of 4,5-Dihydroxypyrimidine-6-Carboxamide Inhibitors of Influenza Virus Endonuclease.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H41 D108 E119 I120 H41 D89 E100 I101
BS02 MN A E80 D108 E61 D89
BS03 GY4 A Y24 E26 H41 E80 E119 K134 Y24 E26 H41 E61 E100 K115
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:5wct, PDBe:5wct, PDBj:5wct
PDBsum5wct
PubMed29215062
UniProtC3W5S0

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