Structure of PDB 5wcl Chain A

Receptor sequence
>5wclA (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQ
NPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKFKRPTLRR
VRISADAMMQALLGARAKGH
3D structure
PDB5wcl Structures reveal details of small molecule binding to cardiac troponin.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9XG A L41 M60 F77 M80 R83 T142 L41 M60 F77 M80 R83 T97 PDBbind-CN: -logKd/Ki=4.52,Kd=30uM
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Cellular Component
GO:0005861 troponin complex

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:5wcl, PDBe:5wcl, PDBj:5wcl
PDBsum5wcl
PubMed27825981
UniProtP19429;
P63316|TNNC1_HUMAN Troponin C, slow skeletal and cardiac muscles (Gene Name=TNNC1)

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