Structure of PDB 5wb2 Chain A

Receptor sequence
>5wb2A (length=421) Species: 10359 (Human betaherpesvirus 5) [Search protein sequence]
DEDATPCVFTDVLNQSKPVTLFLYGVVFLFGSIGNFLVIFTITWRRRIQC
SGDVYFINLAAADLLFVCTLPLWMQYLLDHNSLASVPCTLLTACFYVAMF
ASLCFITEIALDRYYAIVYMRYRPVKQACLFSIFWWIFAVIIAIPHFMVV
TKKDNQCMTDYDYLEVSYPIILNVELMLGAFVIPLSVISYCYYRISRIVA
VSQSRHKGRIVRVLIAVVLVFIIFWLPYHLTLFVDTLKLLKWISSSCEFE
RSLKRALILTESLAFCHCCLNPLLYVFVGTKFRQELHCLLAEPRGSQVQL
VESGGGLVRPGGSLRLSCAASGSIFTIYAMGWYRQAPGKQRELVARITFG
GDTNYADSVKGRFTISRDNAKNAVYLQMNSLKPEDTAVYYCNAEETIVEE
ADYWGQGTQVTVSSRALEVLF
3D structure
PDB5wb2 Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLR A S268 R271 A272 L275 T276 S252 R255 A256 L259 T260
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004950 chemokine receptor activity
Biological Process
GO:0006935 chemotaxis
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5wb2, PDBe:5wb2, PDBj:5wb2
PDBsum5wb2
PubMed29882741
UniProtP69333|US28_HCMVT G-protein coupled receptor homolog US28 (Gene Name=US28)

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