Structure of PDB 5w99 Chain A

Receptor sequence
>5w99A (length=319) Species: 35762 (Planobispora rosea) [Search protein sequence]
TWRRFDVAYHDPDLDRLILAARPLLSESPGRSWFQRHWVRGPHLELWFDH
PEPSWERVREVLGTHLRAHPSRTRIDPDRLLPQHRRLALAEQIDEPLLPF
YDDNTLHRAVPRSRVHVLGSAAAEDLFHDFHAAASTAAFDQLDAVVAGES
RLGLAFELMIAAAHAHAEGGITGGFVSFRSHAEAFLAGAAGLRERWEAEY
RTRAEALRAQVAAVVTGTPRGRAWTGLLDGFAGRGDELIASGALTPDTEF
HRALRANRTWHDEVLRSPSFRRYRLLLNLTYLQMSRLGVTAVQRSLLCHF
AASAVEEEYGVSAIEIAVG
3D structure
PDB5w99 Structural insights into enzymatic [4+2] aza-cycloaddition in thiopeptide antibiotic biosynthesis.
ChainA
Resolution1.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 A1V A E169 G174 V177 S178 S181 H182 L266 N269 T271 W272 V276 F282 R286 I328 G331 E168 G173 V176 S177 S180 H181 L254 N257 T259 W260 V264 F270 R274 I316 G319 PDBbind-CN: -logKd/Ki=4.68,Kd=21uM
External links