Structure of PDB 5w90 Chain A

Receptor sequence

>5w90A (length=263) Species: 464 (Fluoribacter gormanii) [Search protein sequence]

AYPMPNPFPPFRIAGNLYYVGTDDLASYLIVTPRGNILINSDLEANVPMI
KASIKKLGFKFSDTKILLISHAHFDHAAGSELIKQQTKAKYMVMDEDVSV
ILSGGKSDFHYANDSSTYFTQSTVDKVLHDGERVELGGTVLTAHLTPGHT
RGCTTWTMKLKDHGKQYQAVIIGSIGVNPGYKLVDNITYPKIAEDYKHSI
KVLESMRCDIFLGSHAGMFDLKNKYVLLSKGQNNPFVDPTGCKNYIEQKA
NDFYTELKKQETG

3D structure

PDB

5w90 Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril.

Chain

Resolution

1.78 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	H90 H92 D94 H95 H168 Y200 H234
Catalytic site (residue number reindexed from 1)	H71 H73 D75 H76 H149 Y181 H215
Enzyme Commision number	3.5.2.6: beta-lactamase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	A	D94 H95 H234	D75 H76 H215
BS02	ZN	A	H90 H92 H168	H71 H73 H149

External links

PDB	RCSB:5w90, PDBe:5w90, PDBj:5w90
PDBsum	5w90
PubMed	12507470
UniProt	Q9K578

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