Structure of PDB 5w7x Chain A

Receptor sequence
>5w7xA (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
GGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQL
RIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILS
I
3D structure
PDB5w7x Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
ChainA
Resolution2.005 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R27 G28 P29 I33 T34 K36 V38 S39 R40 H58 R25 G26 P27 I31 T32 K34 V36 S37 R38 H56
Gene Ontology
Molecular Function
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006302 double-strand break repair

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5w7x, PDBe:5w7x, PDBj:5w7x
PDBsum5w7x
PubMed29059378
UniProtQ8IW19|APLF_HUMAN Aprataxin and PNK-like factor (Gene Name=APLF)

[Back to BioLiP]