Structure of PDB 5w55 Chain A

Receptor sequence
>5w55A (length=123) Species: 9606 (Homo sapiens) [Search protein sequence]
TNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELP
3D structure
PDB5w55 Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG048
ChainA
Resolution1.354 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 X30 A W81 P82 L92 L94 Y139 N140 W39 P40 L50 L52 Y97 N98
External links
PDB RCSB:5w55, PDBe:5w55, PDBj:5w55
PDBsum5w55
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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