Structure of PDB 5w4s Chain A

Receptor sequence
>5w4sA (length=139) Species: 10116 (Rattus norvegicus) [Search protein sequence]
HTEKRGRIYLKAEVTDEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDP
KNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRND
FMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEG
3D structure
PDB5w4s Structural Basis of Protein Kinase C alpha Regulation by the C-Terminal Tail.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.13: protein kinase C.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y195 K197 N206 K209 K211 K213 E243 W245 W247 R249 R252 Y41 K43 N52 K55 K57 K59 E89 W91 W93 R95 R98
BS02 CA A D187 D193 D246 W247 D248 D33 D39 D92 W93 D94
BS03 CA A M186 D187 D246 D248 D254 M32 D33 D92 D94 D100
External links
PDB RCSB:5w4s, PDBe:5w4s, PDBj:5w4s
PDBsum5w4s
PubMed29642029
UniProtP05696|KPCA_RAT Protein kinase C alpha type (Gene Name=Prkca)

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