Structure of PDB 5w0m Chain A

Receptor sequence
>5w0mA (length=372) Species: 9606 (Homo sapiens) [Search protein sequence]
LEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQD
FPGTKLSLFGSSKNGFGFKQSDLAVCMTINGLETAEGLDCVRTIEELARV
LRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSA
YSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNP
PVIPVLQEIYPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGL
LRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLGAG
LSRKMTNFIMKAFINGRRVFGIPVKGFPKDYPSKMEYFFDPDVLTEGELA
PNDRCCRICGKIGHFMKDCPMR
3D structure
PDB5w0m Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
ChainA
Resolution2.298 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A F1045 G1046 I1099 A1102 K1103 V1104 N1124 N1130 S1164 Y1171 L1288 A1290 R1345 I1353 G1354 F59 G60 I113 A116 K117 V118 N138 N144 S178 Y185 L297 A299 R354 I362 G363
BS02 ZN A C1347 C1350 H1355 C1360 C356 C359 H364 C369
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5w0m, PDBe:5w0m, PDBj:5w0m
PDBsum5w0m
PubMed28671666
UniProtQ5VYS8|TUT7_HUMAN Terminal uridylyltransferase 7 (Gene Name=TUT7)

[Back to BioLiP]