Structure of PDB 5w0b Chain A

Receptor sequence
>5w0bA (length=334) Species: 9606 (Homo sapiens) [Search protein sequence]
QLEPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQ
DFPGTKLSLFGSSKNGFGFKQSDLAVCMTINGLETAEGLDCVRTIEELAR
VLRKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLS
AYSAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRN
PPVIPVLQEICGKNTESVGQLWLGLLRFYTEEFDFKEHVISIRRKSLLTT
IVIEDPFDLNHNLGAGLSRKMTNFIMKAFINGRRVFGIPGFPKDYPSKME
YFFDPDVLTEGELAPNDRCCRICGKIGHFMKDCP
3D structure
PDB5w0b Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
ChainA
Resolution2.614 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C1347 C1350 H1355 C1360 C320 C323 H328 C333
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5w0b, PDBe:5w0b, PDBj:5w0b
PDBsum5w0b
PubMed28671666
UniProtQ5VYS8|TUT7_HUMAN Terminal uridylyltransferase 7 (Gene Name=TUT7)

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